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The Effect of Obesity on Leptin and Some Biochemical Parameters in Salah Al-din  Governorate

Marwa Abdul Salam Kader

Department of Biology , Science College , Tikrit University, Tikrit , Iraq

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Abstract

This study was designed in order to estimate the effect of obesity on leptin concentration and some biochemical parameters of obese individuals in Salah Al-din government. The study involved (40) blood samples which divided into two groups:group one: healthy individuals (BMI from 19.0 to 24.9 kg/m2, n=(20)) as control group and group two: samples from obese  as BMI ≥30.0 kg/m2  n =(20). Obtained from healthy and obese individuals from both genders.  The results of this study showed a significant increase in leptin concentrations (P≤ 0.05) in obese group in comparison with control group; and there was a significant increase in the activity of Aspartate amino transferase (AST), Alanine amino transferase (ALT) and also in the concentrations of  lipid profile:  Cholesterol, Triglyceride, Low density lipoprotein-cho (LDL) and Very low density lipoprotein-cho (VLDL) of obese group in comparison with control group. While there no significant differences in a concentration of High density lipoprotein-cho (HDL) of obese group in comparison with control group.

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